Biotechs, regional banks, and ETFs are top bearish targets as hedge funds borrowing surges

Hedge funds are diving back into aggressive short positions, pushing gross leverage — the total amount of borrowed capital used to amplify bets — to a record high, according to the latest Hedge Fund Trend Monitor from Goldman Sachs Prime Services.

The new data shows a dramatic increase in short selling, particularly in exchange-traded funds (ETFs) and sector-specific stocks like biotechnology firms and regional financial institutions.

Key Stats From the Report:

  • $218 billion in ETF short positions
  • $948 billion in short positions in individual stocks
  • The surge in ETF shorting marks the largest monthly increase in over 10 years

What’s Driving the Trend?

The renewed bearish stance reflects growing uncertainty in the markets — especially around interest rate expectations, fragile financial institutions, and the underperformance of biotech.

Shorting involves selling borrowed stock with the aim of buying it back cheaper — and profiting from the decline. The strategy becomes more attractive in volatile or overvalued sectors.

Sector Focus: Biotech and Banks

According to Goldman’s analysis, hedge funds are aggressively shorting:

  • Biotech stocks, likely due to poor earnings, rising costs, and low funding visibility
  • Regional financials, which remain under pressure post-bank-crisis and amid tightening credit conditions

What Is Gross Leverage?

Gross leverage measures the total exposure (long + short) relative to hedge fund capital. A rising gross leverage indicates hedge funds are borrowing more to amplify both bullish and bearish bets — a sign of increased conviction, but also heightened risk.

What This Means for Markets

High short interest can signal:

  • Bearish sentiment among institutions
  • Potential for short squeezes if sentiment rapidly shifts
  • Increased volatility in the sectors being targeted

Whether this is smart hedging or a warning of further downside remains to be seen — but one thing is clear: hedge funds are gearing up for a choppy ride.

Disclosure: This article does not represent investment advice. The content and materials featured on this page are for educational purposes only.

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